TY - BOOK AU - Little,Melvyn TI - Recombinant Antibodies for Immunotherapy [ electronic resource ] SN - 9780511596773 ( e-book ) U1 - 615.37 21 PY - 2009/// CY - Cambridge PB - Cambridge University Press KW - Biotechnology KW - Microbiology and Immunology KW - Life Sciences KW - Electronic books N2 - Recombinant Antibodies for Immunotherapy provides a comprehensive overview of the field of monoclonal antibodies (mAbs), a market that has grown tremendously in recent years. Twenty-five articles by experienced and innovative authors cover the isolation of specific human mAbs, humanization, immunogenicity, technologies for improving efficacy, 'arming' mAbs, novel alternative Ab constructs, increasing half-lives, alternative concepts employing non-immunoglobulin scaffolds, novel therapeutic approaches, a market analysis of therapeutic mAbs, and future developments in the field. The concepts and technologies are illustrated by examples of recombinant antibodies being used in the clinic or in development. This book will appeal to both newcomers and experienced scientists in the field, biology and biotechnology students, research and development departments in the pharmaceutical industry, medical researchers, clinicians, and biotechnology investors UR - https://doi.org/10.1017/CBO9780511596773 ER -