Includes bibliographical references and index.

Contents
Front Matter
Copyright Page
Preface
Contributors
Introduction
Part I Nature of psychiatric illness
Kenneth S. Kendler and Josef Parnas
Section 1 Clinical significance and disability in psychiatric illness
1 Introduction to “Clinical significance, disability, and biomarkers: Shifts in thinking between DSM-IV and DSM-5”
Kenneth S. Kendler
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2 Clinical significance, disability, and biomarkers: Shifts in thinking between DSM-IV and DSM-5
Derek Bolton
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3 Distinguishing but not dissociating psychiatric disorder and impairment in functioning: Bolton, Hume, and sentiment
Peter Zachar
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Section 2 Psychometric models in psychiatric nosology
4 Introduction to “The hard question in psychiatric nosology”
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Expand5 The hard question in psychiatric nosology
Eric Turkheimer
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6 Representation and explanation in psychometric modeling
Denny Borsboom
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Section 3 Obsessive-compulsive disorders in DSM-5
7 Introduction to “Obsessive-compulsive and related disorders in DSM-5, ICD-11, and RDoC: Conceptual questions and practical solutions”
Kenneth S. Kendler
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Expand8 Obsessive-compulsive and related disorders in DSM-5, ICD-11, and RDoC: Conceptual questions and practical solutions
Dan J. Stein
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Expand9 “A messy business”: Balancing considerations in revising the psychiatric nosology
Miriam Solomon
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Section 4 Network models of psychiatric disorders
10 Introduction to “Mental disorders, network models, and dynamical systems”
Kenneth S. Kendler
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Expand11 Mental disorders, network models, and dynamical systems
Denny Borsboom
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12 I bet on Borsboom
Eric Turkheimer
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Part II Reification, epidemics, and individual symptoms
Kenneth S. Kendler and Josef Parnas
Section 5 Reification of mental illness
13 Introduction to “On reification of mental illness: Historical and conceptual issues from Emil Kraepelin and Eugen Bleuler to DSM-5”
Josef Parnas
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Expand14 On reification of mental illness: Historical and conceptual issues from Emil Kraepelin and Eugen Bleuler to DSM-5
Paul Hoff
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15 Reification of mental illness: Some considerations
Dan J. Stein
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Section 6 Psychiatric epidemics
16 Introduction to “Factors in the development of psychiatric epidemics”
Kenneth S. Kendler
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Expand17 Factors in the development of psychiatric epidemics
Michael B. First
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18 Diagnostic epidemics and diagnostic disarray: The issue of differential diagnosis
Josef Parnas
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Section 7 Culture-bound psychiatric syndromes
19 Introduction to “Description and explanation of the culture-bound syndromes”
Kenneth S. Kendler
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Expand20 Description and explanation of the culture-bound syndromes
Dominic Murphy
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21 Reflections on culture-bound syndromes
Paul S. Appelbaum
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Section 8 The coming and going of Asperger’s syndrome
22 Introduction to “On the appearance and disappearance of Asperger’s syndrome”
Kenneth S. Kendler
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Expand23 On the appearance and disappearance of Asperger’s syndrome
Miriam Solomon
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24 Impact of “severity decategorization” in DSM-5
Michael B. First
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Section 9 Auditory verbal hallucinations
25 Introduction to “The ontology and epistemology of symptoms: The case of auditory verbal hallucinations in schizophrenia”
Kenneth S. Kendler
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Expand26 The ontology and epistemology of symptoms: The case of auditory verbal hallucinations in schizophrenia
Josef Parnas and Annick Urfer-Parnas
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Expand27 Comment on “The ontology and epistemology of symptoms: The case of auditory verbal hallucinations in schizophrenia”
Paul Hoff
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Part III Epistemic iteration
Kenneth S. Kendler and Josef Parnas
Section 10 Epistemic iteration in scientific taxonomies
28 Introduction to “Epistemic iteration and natural kinds: Realism and pluralism in taxonomy”
Josef Parnas
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Expand29 Epistemic iteration and natural kinds: Realism and pluralism in taxonomy
Hasok Chang
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30 Psychiatric nosology, epistemic iteration, and pluralism
Kenneth S. Kendler
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Section 11 Problems in the validation of psychiatric diagnoses
31 Introduction to “Validity and the causal structure of a disorder”
Kenneth S. Kendler
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Expand32 Validity and the causal structure of a disorder
John Campbell
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Expand33 Saving the explananda
Georg Repnikov and Dominic Murphy
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Section 12 Personality disorders in DSM-5
34 Introduction to “Epistemic iteration or paradigm shift: The case of personality disorder”
Kenneth S. Kendler
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Expand35 Epistemic iteration or paradigm shift: The case of personality disorder
Peter Zachar
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Expand36 Why we should be realists about psychiatric disorders— reply to Peter Zachar
John Campbell
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Section 13 The progressive validation of medical and psychiatric disorders
37 Introduction to “Progressive validation of psychiatric syndromes: The example of panic disorder”
Josef Parnas
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Expand38 Progressive validation of psychiatric syndromes: The example of panic disorder
Kenneth S. Kendler
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Expand39 Comments on “Progressive validation of psychiatric syndromes: The example of panic disorder”
Kenneth F. Schaffner and Kathryn Tabb
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Part IV Descriptive to etiologic and living document
Kenneth S. Kendler and Josef Parnas
Section 14 Descriptive to etiologic in psychiatric nosology
40 Introduction to “Causal pathways, random walks and tortuous paths: Moving from the descriptive to the etiological in psychiatry”
Josef Parnas
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Expand41 Causal pathways, random walks, and tortuous paths: Moving from the descriptive to the etiological in psychiatry
Kathryn Tabb and Kenneth F. Schaffner
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Expand42 Comments on “Causal pathways, random walks, and tortuous paths: moving from the descriptive to the etiological in psychiatry”
Hasok Chang
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Section 15 Progress in psychiatric research
43 Introduction to “What is progress in psychiatric research?”
Kenneth S. Kendler
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Expand44 What is progress in psychiatric research?
Stephan Heckers
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45 Comments on “What is progress in psychiatric research?”
Derek Bolton
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Section 16 After DSM-5
46 Introduction to “DSM-5.1: Perspectives on continuous improvement in diagnostic frameworks”
Kenneth S. Kendler
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Expand47 DSM-5.1: Perspectives on continuous improvement in diagnostic frameworks
Paul S. Appelbaum
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Expand48 How do we improve the DSM?
Stephan Heckers
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End Matter
Index

Abstract
This book contains, in addition to an introduction, sixteen chapters, each with its own introduction and discussion, that review various issues within psychiatric nosology from clinical, historical and particularly philosophical perspectives. The contributors to this book include major psychiatric researchers, clinicians, historians and especially nosologists (including several leaders of the DSM-5 effort and the DSM Steering Committee that will be guiding future revisions in DSM for the foreseeable future), psychologists with a special interest in psychiatric nosology and philosophers with a wide range of orientations. The book is organized into four major sections. The first explores the nature of psychiatric illness and the ways in which define it including clinical and psychometric perspectives. The second section examines problems in the reification of psychiatric diagnostic criteria, the problem of psychiatric epidemics and the nature and definition of individual symptoms. The third session explores the concept of epistemic iteration as a possible governing conceptual framework for the revision efforts for official psychiatric nosologies such as DSM and ICD and the problems of validation of psychiatric diagnoses. The final session explores how we might move from the descriptive to the etiologic in psychiatric diagnoses, the nature of progress in psychiatric research and the possible benefits of moving to a living document (or continuous improvement) model for psychiatric nosologic systems. The organization of the book—with its introduction and comments—well captures the dynamic cross-disciplinary interactions that characterize the best work in the philosophy of psychiatry.