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01799nam a22002537a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
IN-MiVU |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20191126135242.0 |
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| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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180518s2010 xxu||||go|||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780198569237 ( e-book ) |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
MAIN |
| Language of cataloging |
eng |
| Transcribing agency |
IN-MiVU |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Vijg, Jan |
| 245 00 - TITLE STATEMENT |
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| Title |
Aging of the Genome : |
| Remainder of title |
The dual role of DNA in life and death [ electronic resource ] / |
| Statement of responsibility, etc. |
by Jan Vijg. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Name of publisher, distributor, etc. |
Oxford Scholarship Online , |
| Date of publication, distribution, etc. |
2010 |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides a synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change. |
| 650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Genetics and Molecular Biology |
| 650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Physiology |
| 650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Zoology |
| 655 #4 - INDEX TERM--GENRE/FORM |
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| Genre/form data or focus term |
Electronic books |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://doi.org/10.1093/acprof:oso/9780198569237.001.0001">https://doi.org/10.1093/acprof:oso/9780198569237.001.0001</a> |
| Link text |
https://doi.org/10.1093/acprof:oso/9780198569237.001.0001 |
| Public note |
View to click |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
|
| Koha item type |
E-Book |
